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Intervention: In African-American female adolescents with hepatitis B (P), how does
acetaminophen (I) compared to ibuprofen (C) affect liver function (O)?
Therapy: In children with spastic cerebral palsy (P), what is the effect of splinting and casting(I)
compared to constraint- induced therapy (C) on two-handed skill development (O)?
1) For patients 65 years and older (P), how does the use of an influenza vaccine (I) compared to
not received the vaccine (C) influence the risk of developing pneumonia (O) during flu season
2) In patients who have experienced an acute myocardial infarction (P), how does being a
smoker (I) compared to a non-smoker (C) influence death and infarction rates (O) during the
first 5 years after the myocardial infarction (T)?
Diagnosis: In middle-aged males with suspected myocardial infarction (P), are serial 12-lead
ECGs (I) compared to one initial 12-lead ECG (C) more accurate in diagnosing an acute
myocardial infarction (O)?
Etiology: Are 30- to 50-year-old women (P) who have high blood pressure (I) compared with
those without high blood pressure (C) at increased risk for an acute myocardial infarction (O)
during the first year after hysterectomy (T)?
Meaning: How do young males (P) with a diagnosis of below the waist paralysis (I) perceive
their interactions with their romantic significant others (O) during the first year after their
diagnosis (T)?

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